Pharmacokinetics Scientist

Date:  Feb 6, 2024
Department:  Pre-Clinical
Job Type:  Direct Employee
Team:  R&D, Pharmacovigilance & Regulatory Affairs
Contract Type:  Permanent

Parma, IT

About us

Based in Parma, Italy, Chiesi is an international research-focused pharmaceutical and healthcare group with over 85 years’ experience, operating in 30 countries with more than 6,000 employees (Chiesi Group). To achieve its mission of improving people’s quality of life by acting responsibly towards society and the environment, the Group researches, develops and markets innovative drugs in its main therapeutic areas: Discover more here

We are proud to be the largest global pharmaceutical group to be awarded B Corp Certification, a recognition of high social and environmental standards. We are a reliable company that adopts and promotes a transparent and ethical behavior at all levels.

We believe that the success of Chiesi is built and shaped by our people and our strong set of shared Values and Behaviors. Our people make a critical difference to our success, which is why it is vital that we attract and retain the right talent who will continue to enrich our culture by living and breathing our values and behaviors.

We are committed to embrace diversity, inclusion and equal opportunities. In fact, we are a global family made up of different cultures, different genders, generations, ethnicities, abilities, sexual identities and many other enriching diversities. 


Chiesi Research & Development

Our R&D team represents a fundamental asset for the business. It is divided into integrated functional areas focusing on pipeline projects including discovery and preclinical research, chemical manufacturing and controls, drug delivery technology, clinical development, regulatory affairs, pharmacovigilance, intellectual property, quality assurance, R&D project and portfolio management.  Headquartered in the new purpose-built and fully integrated Research and Development Centre in Parma (Italy), the team also has important operations in Paris (France), Chippenham (UK), Cary (US), Stockholm (Sweden) and Toronto (Canada).


Who we are looking for


PK and PK/PD modeling and simulation expert in the pre-clinical Pharmacokinetic, Biochemistry & Metabolism department

Main Responsibilities

  • The candidate should cover the position of preclinical DMPK expert in dynamic cross-functional teams conducting PK and PK/PD modelling and simulation analysis in preclinical drug discovery finalized to evaluate NCEs human therapeutic windows.
  • Together with the ADME/PK expert role in discovery teams, is requested the design of PK/PD models and the development of mathematical modelling approaches to link pre-clinical and clinical data by the identification of the appropriate PK and PD drivers related to efficacy and safety. Models should be developed as compartmental models and as whole body physiologically-based PK models, evaluated according to statistical tests and used applying the translational medicine principles.
  • Good interaction is requested with clinical departments in all the phases to refine drug projection, knowledge and propose input and hypotheses on protocol designs.


Experience Required

At leasr 3 years previous experience in Pharma with significant experience in the following areas: Pharmacokinetic or pharmacokinetic-pharmacodynamic modelling, physiologically based pharmacokinetic modelling


Master Degree




Technical Skills

  • Strong non-compartmental analysis experience
  • Experience using Phoenix WinNonlin or similar software to conduct non-compartmental and compartmental analysis.
  • Mathematical and statistical background
  • Mathematical modelling with experience in modelling biological data
  • Demonstrated understanding of the drug development process
  • Ability to interact and collaborate with scientists from various disciplines and functional areas
  • Problem-solving ability applying ADME/PK principles to mitigate project issues


Soft Skills

  • Analytical skills
  • Communication skills
  • Team working
  • Quality orientation
  • Problem solving

What we offer

You would join a dynamic, fast-growing, challenging and friendly environment.
In Chiesi we firmly believe that our people are our most valuable asset, that is why we invest in continuous training, learning and development. Therefore, we strive to continuously promote and satisfy development needs, paying particular attention to the quality of our working environment and to collective well-being.
We want our people to come to work happy every day, and we know how important it is to find the right work-life balance in order to be able to give our best. That is why we offer flexible working approach, remote working, support in the relocation process, tax assistance service for foreign colleagues and many other people-care services.

Discover all our opportunities